Rohit Loomba MD, Clinical/Scientific Advisor

Dr. Rohit Loomba is a leading expert in translational research and innovative clinical trial design in nonalcoholic fatty steatohepatitis (NASH) and fatty liver disease (NAFLD), a precursor to NASH.  He is a principle investigator for Gilead’s first-in-class ASK1 inhibitor program in NASH.

 

Dr. Loomba is the founding director of the University of California, San Diego NAFLD Translational Research Unit where his team is conducting cutting edge research in all aspects of NAFLD including non-invasive biomarkers, genetics, epidemiology, clinical trial design, imaging end-points, and integrated OMICs using microbiome, metabolome and lipidome. This integrated approach has led to several innovative applications. He follows one of the largest cohorts of well-characterized patients with NAFLD and applies evidence-based medicine to answer clinically relevant questions to improve management of patients with chronic liver disease.

 

He leads a multidisciplinary team of trainees, nurses, clinicians and scientists in conducting cutting edge translational research in liver disease. Dr. Loomba and his collaborators are leading a major effort into non-invasive biomarkers especially imaging modalities for assessment of fat, inflammation, cell injury and fibrosis in patients with chronic liver diseases, and developing therapies for the treatment of NASH and NASH related fibrosis.

Scott Friedman MD, Clinical/Scientific Advisor

Scott L. Friedman is an American scientist, professor and physician who works in the field of hepatology. Friedman has conducted pioneering research into the underlying causes of scarring, or fibrosis, associated with chronic liver disease, by characterizing the key fibrogenic cell type, the hepatic stellate cell. His laboratory has also discovered a novel tumor suppressor gene, KLF6 that is inactivated in a number of human cancers including primary liver cancer.  Friedman is the Fishberg Professor of Medicine, and Chief of the Division of Liver Diseases, Mount Sinai School of Medicine in New York. Friedman has two children, a son, Leor Friedman, and a daughter, Yael Friedman.

ADVISORS

 
 
 

Seal Rock Therapeutics - 500 Yale Ave N, Seattle, WA 98109, USA - info@sealrocktx.com - 206.401.5086